Pharmaceutical Dosage Forms: Capsules

Authors : Larry L. Augsburger, Stephen W. Hoag
Edition : 1
Year : 2018
Description :

Pharmaceutical Dosage Forms: Capsules covers the development, composition, and manufacture of capsules. Despite the important role that capsules play in drug delivery and product development, few comprehensive texts on the science and technology of capsules have been available for the research and academic environments. This text addresses this gap, discussing how capsules provide unique capabilities and options for dosage form design and formulation.

Content: 

• Advances in capsule formulation and filling 
• An introduction to two-piece hard capsules and their marketing benefits 
• Hard shell capsules in clinical trials 
• Manufacture of capsule shells 
• Non-gelatin based capsules 
• Hard shell capsule filling machines 
• Instrumented capsule filling machines and filling machine simulators 
• Dry-fill formulation and filling technology 
• Plug formation 
• Modeling powder filling during encapsulation / Ammar Khawam --
• Scaling-up and transfer of hard shell formulations across machine types 
• Modified release delivery systems : extended release capsule platform 
• Analytical testing and evaluation of capsules 
• Rheological aspects of capsule shell excipients and the manufacture of encapsulated formulations 
• Quality-by-design (QBD) for capsule formulation and process development : regulatory science developments, scientific case studies, and future challenges 

Link Download :   http://dowf41E197